N.B. As an Amazon Associate I earn from qualifying purchases. This article contains numerous Amazon affiliate links, and not only those: by using them you support my work at no extra cost to you. Thank you!
Some people need a travel backpack for a weekend getaway, some are about to travel around the world, and others – like digital nomads – decide to sell everything and make a backpack their new home.
Choosing the right travel backpack can be more complicated than you think. There are loads of options on the market and everyone has different needs, but after trying out plenty of different ones over the years, I think I’ve figured out what works and what doesn’t.
With this guide I’ll try to help you make the best choice.
Quick menu
Be warned: going up and down stairs with a rolling suitcase is a real nightmare, one hand is always occupied the whole time you’re on the move, and walking through crowded places can be extremely frustrating.
The only upside is that you can carry luggage that isn’t exactly light without too much trouble. But the real challenge is always managing to travel light!
The main problem with a hiking backpack is the opening. They all load from the top and have no front opening that lets you easily get to everything inside. So you’ll be forced to empty it out every single time you’re looking for something.
On top of that, there are loads of useless straps designed for carrying ice axes, trekking poles, sleeping bags etc. etc., no problem until those straps get snagged on something!
For the security freaks out there, these backpacks can’t be locked with a padlock, because the main compartment has no zippers and closes with a drawstring.
These backpacks are a great alternative for people who can’t give up the convenience of a rolling suitcase or who, for whatever reason, can’t cover long distances on foot with a backpack on their shoulders.
The biggest downside of these backpacks is the frame the wheels are attached to, which makes them much heavier, less comfortable and more expensive than similar backpacks without wheels.
Also, in some developing countries, the roads and sidewalks often don’t make it easy to use them like a rolling suitcase.
Basically, I don’t think it’s the ideal solution for everyone, but it can definitely be for some people or types of trips. My advice, as always, is to travel light and not need wheels to carry your luggage.

Let’s start with a mistake that almost everyone makes: bringing more than you need.
The length of the trip doesn’t matter… clothes can be washed! A week or a month makes no difference to the size of your backpack.
If you spend every night in a hostel or a hotel – so you don’t need camping gear – 40-50 liters of volume will be more than enough to carry everything you need. Life as a backpacker will be so much easier and more comfortable, giving you the highest degree of freedom.
This size is ideal especially for anyone who wants to travel with a single backpack that falls into the “carry-on” category. It’s big enough to travel anywhere as long as you’re not going through extremely different climates. Paired with a smaller 10-20 liter backpack, it’s my favorite solution.
Unfortunately, there’s no standard size for the famous “carry-on”. Every airline has its own restrictions on height, width, depth and weight, so some backpacks may be slightly shorter, wider or narrower.
The nice thing about backpacks is that they aren’t exactly rigid and can be squeezed into the sizer frames at boarding (if you’re even asked to do it). Pay attention to the weight – they’re usually much stricter about it – the limit is almost always around 10kg.
Here you can find an up-to-date list for almost all airlines.
In any case, never go over 60L unless you have special needs.
Let’s look at the factors to take into account:
Front opening: A front opening combines the convenience of a rolling suitcase with the practicality of a backpack, taking the best of both. Whenever you need to take something out of your backpack you won’t have to empty the whole thing, and everything will be within reach just like in a suitcase. Once you’ve tried it, you won’t be able to do without it.
Water resistance: Nobody likes ending up with the contents of their backpack completely soaked, but note that “water or splash resistance” doesn’t mean the backpack is completely waterproof.
Durability: When you’re traveling, your backpack is your home! Invest in a good-quality backpack. Nobody likes having to replace their backpack after every trip, let alone having to replace it during the trip itself.
Comfort: Make sure you buy a backpack that fits your body, taking height and gender into account. Other features that affect comfort are the padded shoulder straps, the hip belt and a ventilated back panel. Remember to adjust everything properly, this video explains how to do it. Women should consider buying a backpack with curved shoulder straps, especially if they have a large bust.
Versatility: Especially if you decide to travel with just one backpack, consider buying one with a small detachable daypack attached. Alternatively, you could pair the big backpack with a super light, packable daypack of about 15 – 20 liters, useful for getting around and exploring.
Security: Are you a security freak? Starting from the fact that I strongly believe that safety while traveling depends mostly on everyone’s common sense, a few precautions could be making sure that the zippers can be locked with a padlock (ideally TSA-approved), that there’s some secret pocket or hidden compartment where you can put your most important documents, that the outer material is cut-resistant to discourage would-be thieves, and that the backpack isn’t a flashy color that draws too much attention.
Below I list what I think are excellent choices for quality and price, keeping in mind that there are countless products on the market and listing them all is impossible. Here you’ll find my video review (in Italian, but you can turn on the subtitles).

N.B. Osprey has released a new version of the Farpoint 40, which you can find at this link. The main differences are: a new back panel adjustment system (there are no longer different sizes) and the padded laptop compartment is now at the back. You can find a great video at this page.
It’s probably the most popular travel backpack in the world, the quality of the materials is excellent and it offers great value for money.
Osprey Fairview 40 is essentially the same backpack, designed specifically to give women maximum comfort.
Features

N.B. Osprey has also released a new version of the Farpoint 55, which you can find at this link. You can find a great video at this page, while here you’ll find my video review of the old model (in Italian, but you can turn on the subtitles).
Osprey Farpoint 55 is essentially a Farpoint 40 with a 15-liter daypack attached to the front. That makes it extremely versatile.
Osprey Farpoint 55 Trek → It’s a single backpack, so it can’t be used as carry-on. As the name suggests, it’s designed for people who want a backpack that’s also suitable for trekking.
Osprey Fairview 55 → same backpack but for women.
And in case you need some extra space, I recommend taking a look at Osprey Farpoint 70. It’s basically the same model, except that the main backpack is about 55 liters while the size of the daypack doesn’t change.
Features

The Kelty Redwing 50 and its little brother, the Kelty Redwing 44, are a hybrid between a travel backpack and a hiking backpack; compared to the Osprey Farpoint it’s more backpack and less suitcase. Here you’ll find my video review (in Italian, but you can turn on the subtitles).
It’s a great alternative especially for people who want a backpack for both traveling and hiking.
Features

A travel backpack with a ton of unique features, ideal in my opinion for anyone who wants to travel with carry-on only, or at least with a single backpack. Given the price, it’s definitely in the premium category and definitely not a budget option. That said, if budget isn’t an issue, I’ve seen a lot of backpacks and I think there’s more than one reason to consider this particular model. Here you’ll find my video review of the backpack and some accessories (in Italian, but you can turn on the subtitles). There’s also a smaller 30-liter version with very similar features (Travel Backpack 30L).
Features

Ideal for short trips. It fully meets the carry-on size limits (55x40x20).
The lack of a hip belt and a ventilated back panel makes it a backpack that isn’t suited to carrying around for long distances. Basically, it’s a suitcase without wheels but with shoulder straps. Here you’ll find my video review (in Italian, but you can turn on the subtitles).
Features

If you think a wheeled backpack is the best choice for you, then go for the Osprey Meridian. Like the Osprey Farpoint, it has a removable daypack on the front of about 16L, which makes it a great all-in-one solution.
Unfortunately it doesn’t have a hip belt, so it isn’t suitable for long walks. If you’re looking for something of the same size, without the removable daypack but with a hip belt, then consider Osprey Sojourn, which is definitely more backpack and less rolling suitcase. If instead you’re looking for a product that can be used as carry-on, then Osprey Ozone should do the trick.
Features

This backpack is ideal for anyone looking for a great hiking/travel backpack with a bit of extra space compared to the previous models. If, however, you want a backpack whose main compartment can be opened completely like the other models we just saw, and you can’t give up the extra space, I recommend taking a look at Osprey Farpoint 70. Here you’ll find my video review (in Italian, but you can turn on the subtitles).
Features
When I travel I always carry a small daypack that I wear on my front, because my valuables are inside and I never want to lose sight of it. The big backpack, on the other hand, which I carry on my back, works as my suitcase, and I have no problem putting it on the roof of a bus or leaving it at the hostel.
If you can’t stand the idea of traveling with two backpacks, you can buy a backpack like the Osprey Farpoint 55, which has the daypack built in, or an ultralight, packable daypack like the Sea to Summit Ultra-Sil and the Osprey Ultralight, which you can simply stow in the big backpack when you don’t need it.
As with the big backpacks, there are tons of options, and in this article I go deeper into the topic, describing what I think are the best travel daypacks.
Here’s the complete list of what to put in your backpack!
I’m a born saver, but especially for long-term trips it’s better to avoid unpleasant surprises and set off with the right gear. When you travel, your backpack is the most important thing, and it’s definitely worth investing some money in a product that will last for years.
Planning a trip? Check out these posts:
Which travel insurance to choose
Which travel backpack to choose
Since I no longer run ads, if you found this article helpful, please consider purchasing your travel insurance through one of the links on this site. Doing so supports my work at no additional cost to you. For EU and UK residents, I recommend True Traveller. For everyone else, I recommend HeyMondo, which offers a 5% discount. Thank you for your support!

For transparency! Some of the links in this article are affiliate links. This means that if you buy any product using one of the links I earn a small commission at no additional cost to you. Don’t be afraid, they’re all products I use and/or would like to use. I don’t recommend products I don’t believe in.